Endocrine Abstracts

Follicle-stimulating hormone (FSH) is essential for primate reproduction, acting via the FSH-receptor (FSHR) which is expressed in Sertoli and granulosa cells only. Despite its highly specific expression pattern, knowledge of the FSHR promoter and transcriptional regulation is still very limited. To gain insights into the regulatory elements controlling FSHR expression we characterized the core promoter activity of all important primate lineages including human. We isolated DN...